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If you have never been to Seattle, the first thing you will notice is the scenery. The city itself sits between the mountains and the water. The setting is amazing. The only negative to this part of the country is the weather. It seems to rain every day. Unlike most cities that pour down rain for a while and then clear up, the rain in Seattle is like a fine mist/drissle all the time. For the sun-worshipers, it can be depressing...but it does add character to the city.
I always stay downtown in Seattle. There are numerous nice hotels downtown and everything you would need is within walking distance. If you stay downtown, you are also close to the tourist attractions including the Space Needle. If you have the time, I would highly recommend a trip to the top of the Space Needle (pictured above). Towering above the city, you get great views of the entire area from the top of the Space Needle.
If you are looking for a great gym in downtown Seattle, then the 24-Hour Fitness on Yale Avenue is a great option. In addition to this gyms reputation for being a very gay gym, it also has great equipment as well. Also, since it is within a few blocks of most of the downtown hotels, it is in a very convenient location as well.